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Sodium, calcium and exocytosis: Confessions of calcified scientists

  • J. Nordmann
  • , M. Lindau
  • , EL L. Stuenkel*
  • *Corresponding author for this work
  • Centre de Neurochimie
  • Biophysics Group
  • Free University of Berlin
  • University of Michigan, Ann Arbor

Research output: Contribution to journal › Article › peer-review

Abstract

Stimulated exocytotic secretion from nerve endings is initiated by an increase in intracellular free calcium concentration. We summarize here our latest findings regarding the temporal relationship between depolarization, elevation of [Ca2+]i and exocytosis in single vertebrate neuroendocrine nerve endings. In addition, we present surprising findings for a regulatory role of intracellular Na+ on exocytosis.

Original languageEnglish
Pages (from-to)15-21
Number of pages7
JournalJournal of Physiology - Paris
Volume86
Issue number1-3
DOIs
Publication statusPublished - 1992
Externally publishedYes

Keywords

  • calcium
  • nerve ending
  • neurosecretion
  • sodium

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