Role of Exosomal MicroRNAs in Cell-to-Cell Communication

  • Bora Tastan
  • , Emre Tarakcioglu
  • , Yelda Birinci
  • , Yongsoo Park
  • , Sermin Genc*
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

16 Citations (Scopus)

Abstract

Exosomes, a type of extracellular vesicle, are small vesicles (30–100 nm) secreted into extracellular space from almost all types of cells. Exosomes mediate cell-to-cell communication carrying various biologically active molecules including microRNAs. Studies have shown that exosomal microRNAs play fundamental roles in healthy and pathological conditions such as immunity, cancer, and inflammation. In this chapter, we introduce the current knowledge on exosome biogenesis, techniques used in exosome research, and exosomal miRNA and their functions in biological and pathological processes.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages269-292
Number of pages24
DOIs
Publication statusPublished - 2022
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume2257
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Cancer
  • Cardiovascular System
  • Central Nervous System
  • Exosome
  • Immune System
  • Inflammation
  • MicroRNA

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