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Risk factors for central lymph node metastasis of patients with papillary thyroid microcarcinoma: A meta-analysis

  • Zeming Liu
  • , Longqiang Wang
  • , Pengfei Yi
  • , Cong Yi Wang
  • , Tao Huang*
  • *Corresponding author for this work
  • Huazhong University of Science and Technology
  • Center for Biomedical Research

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate the risk factors of central lymph node metastasis of papillary thyroid microcarcinoma. Method: Published articles about papillary thyroid microcarcinoma were searched in PubMed, MEDLINE and EMBASE until October 2013 to examine the risky factors of central lymph node metastasis. Software RevMan 5.0 was used for meta-analysis. Results: Within the patients suffering papillary thyroid microcarcinoma underwent thyroidectomy plus prophylactic central lymph node dissection, tumor size, multifocality and capsular invasion have statistically relevant association with central lymph node metastasis, but no relation was observed associated with sex and age. Conclusion: The papillary thyroid microcarcinoma should be considered central lymph node metastasis when tumor size ≥0.5 cm, multifocality and have capsular invasion.

Original languageEnglish
Pages (from-to)932-937
Number of pages6
JournalInternational Journal of Clinical and Experimental Pathology
Volume7
Issue number3
Publication statusPublished - 2014
Externally publishedYes

Keywords

  • Central lymph node metastasis
  • Papillary thyroid carcinoma
  • Risk factors

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