Organizational structure of the transcriptional regulatory network of yeast: Periodic genes

Frank Emmert-Streib; Matthias Dehmer

doi:10.1007/978-3-642-02466-5_12

Organizational structure of the transcriptional regulatory network of yeast: Periodic genes

Frank Emmert-Streib^*
, Matthias Dehmer

^*Corresponding author for this work

Queen's University Belfast
Private University for Health Sciences, Medical Informatics and Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

In this paper we investigate the organizational structure of the transcriptional regulatory network of S. cerevisiae with respect to the connectivity structure of periodic genes. We demonstrate that the giant strongly connected component plays a prominent role serving as central connector for genes experimentally found to be periodically expressed during the cell cycle of yeast. Numerically, we find by randomization of the gene labels that this organizational structure is unlikely to be formed by chance.

Original language	English
Title of host publication	Complex Sciences - First International Conference, Complex 2009, Revised Papers
Pages	140-148
Number of pages	9
Edition	PART 1
DOIs	https://doi.org/10.1007/978-3-642-02466-5_12
Publication status	Published - 2009
Externally published	Yes
Event	1st International Conference on Complex Sciences: Theory and Applications, Complex 2009 - Shanghai, China Duration: 23 Feb 2009 → 25 Feb 2009

Publication series

Name	Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering
Number	PART 1
Volume	4 LNICST
ISSN (Print)	1867-8211

Conference

Conference	1st International Conference on Complex Sciences: Theory and Applications, Complex 2009
Country/Territory	China
City	Shanghai
Period	23/02/09 → 25/02/09

Keywords

Causality
Graph theory
Periodic genes
Randomization
Transcriptional regulatory network

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10.1007/978-3-642-02466-5_12

Cite this

Emmert-Streib, F., & Dehmer, M. (2009). Organizational structure of the transcriptional regulatory network of yeast: Periodic genes. In Complex Sciences - First International Conference, Complex 2009, Revised Papers (PART 1 ed., pp. 140-148). (Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering; Vol. 4 LNICST, No. PART 1). https://doi.org/10.1007/978-3-642-02466-5_12

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title = "Organizational structure of the transcriptional regulatory network of yeast: Periodic genes",

abstract = "In this paper we investigate the organizational structure of the transcriptional regulatory network of S. cerevisiae with respect to the connectivity structure of periodic genes. We demonstrate that the giant strongly connected component plays a prominent role serving as central connector for genes experimentally found to be periodically expressed during the cell cycle of yeast. Numerically, we find by randomization of the gene labels that this organizational structure is unlikely to be formed by chance.",

keywords = "Causality, Graph theory, Periodic genes, Randomization, Transcriptional regulatory network",

author = "Frank Emmert-Streib and Matthias Dehmer",

year = "2009",

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Emmert-Streib, F & Dehmer, M 2009, Organizational structure of the transcriptional regulatory network of yeast: Periodic genes. in Complex Sciences - First International Conference, Complex 2009, Revised Papers. PART 1 edn, Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering, no. PART 1, vol. 4 LNICST, pp. 140-148, 1st International Conference on Complex Sciences: Theory and Applications, Complex 2009, Shanghai, China, 23/02/09. https://doi.org/10.1007/978-3-642-02466-5_12

Organizational structure of the transcriptional regulatory network of yeast: Periodic genes. / Emmert-Streib, Frank; Dehmer, Matthias.
Complex Sciences - First International Conference, Complex 2009, Revised Papers. PART 1. ed. 2009. p. 140-148 (Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering; Vol. 4 LNICST, No. PART 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AB - In this paper we investigate the organizational structure of the transcriptional regulatory network of S. cerevisiae with respect to the connectivity structure of periodic genes. We demonstrate that the giant strongly connected component plays a prominent role serving as central connector for genes experimentally found to be periodically expressed during the cell cycle of yeast. Numerically, we find by randomization of the gene labels that this organizational structure is unlikely to be formed by chance.

KW - Causality

KW - Graph theory

KW - Periodic genes

KW - Randomization

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AN - SCOPUS:68949201343

SN - 3642024653

SN - 9783642024658

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BT - Complex Sciences - First International Conference, Complex 2009, Revised Papers

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Emmert-Streib F, Dehmer M. Organizational structure of the transcriptional regulatory network of yeast: Periodic genes. In Complex Sciences - First International Conference, Complex 2009, Revised Papers. PART 1 ed. 2009. p. 140-148. (Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering; PART 1). doi: 10.1007/978-3-642-02466-5_12

Organizational structure of the transcriptional regulatory network of yeast: Periodic genes

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Keywords

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