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Longitudinal Treatment-Aware Multimodal AI for Dermatology: A Scoping Review

  • Hamad bin Khalifa University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The field of dermatological AI has rapidly advanced from simple single-image classifiers to large, multimodal foundation models. Despite achieving high diagnostic accuracy, current systems mostly analyze a single point in time and do not incorporate patient history or previous treatments. This review explores the evidence for longitudinal, treatment-aware, and multimodal large language model (LLM) approaches in dermatology, with an emphasis on chronic inflammatory conditions such as eczema, acne, psoriasis, and rosacea. Researchers examined five databases, PubMed, ACM, IEEE Xplore, Web of Science, and Scopus, covering studies from 2020 to 2026. Using PRISMA-ScR guidelines, 30 studies were selected from 1,644 citations. The review identifies five key themes: (1) shift from static to longitudinal AI; (2) multimodal vision-language integration; (3) treatment-aware decision support systems; (4) temporal reasoning capabilities; and (5) benchmarks and evaluation methods. Currently, no models combine longitudinal imaging, medication logs, and LLM reasoning specifically for chronic inflammatory skin diseases. This review highlights five major research gaps and calls for longitudinal, treatment-annotated benchmarks to advance progress in the field.

Original languageEnglish
Title of host publicationHealth Sciences Informatics Leads and Empowers the Digital Health Transformation - 24th International Conference on Informatics, Management, and Technology in Healthcare, ICIMTH 2026
EditorsJohn Mantas, Arie Hasman, Parisis Gallos, Reinhold Haux, Konstantinos Karitis
PublisherIOS Press BV
Pages763-767
Number of pages5
ISBN (Electronic)9781643686684
DOIs
Publication statusPublished - 29 Jun 2026
Event24th International Conference on Informatics, Management, and Technology in Healthcare, ICIMTH 2026 - Athens, Greece
Duration: 3 Jul 20265 Jul 2026

Publication series

NameStudies in Health Technology and Informatics
Volume338
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference24th International Conference on Informatics, Management, and Technology in Healthcare, ICIMTH 2026
Country/TerritoryGreece
CityAthens
Period3/07/265/07/26

Keywords

  • Dermatology
  • Longitudinal AI
  • Multimodal Large Language Models
  • Temporal Reasoning
  • Treatment-Aware AI

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