Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
- Felix R. Day
- , Katherine S. Ruth
- , Deborah J. Thompson
- , Kathryn L. Lunetta
- , Natalia Pervjakova
- , Daniel I. Chasman
- , Lisette Stolk
- , Hilary K. Finucane
- , Patrick Sulem
- , Brendan Bulik-Sullivan
- , Tõnu Esko
- , Andrew D. Johnson
- , Cathy E. Elks
- , Nora Franceschini
- , Chunyan He
- , Elisabeth Altmaier
- , Jennifer A. Brody
- , Lude L. Franke
- , Jennifer EHuffman
- , Margaux F. Keller
*Corresponding author for this work
- University of Cambridge
- Genetics of Complex Traits
- University of Exeter
- Department of Public Health and Primary Care
- Department of Biostatistics
- Boston University
- National Heart Lung and Blood Institute’s and Boston University’s Framingham Heart Study
- University of Tartu
- Institute of Molecular and Cell Biology
- Division of Preventive Medicine
- Brigham and Women’s Hospital
- Harvard University
- Erasmus University Rotterdam
- Netherlands Consortium for Healthy Ageing and National Genomics Initiative
- Department of Epidemiology
- Department of Mathematics
- Massachusetts Institute of Technology
- deCODE Genetics
- Broad Institute
- Analytic and Translational Genetics Unit
- Massachusetts General Hospital
- Medical and Population Genetics
- Division of Endocrinology
- Boston Children's Hospital
- Department of Genetics
- Department of Epidemiology
- University of North Carolina at Chapel Hill
- Department of Epidemiology
- Indiana University-Purdue University Indianapolis
- Indiana University Bloomington
- Research Unit Molecular Epidemiology
- Helmholtz Zentrum München - German Research Center for Environmental Health
- Institute of Genetic Epidemiology
- Institute of Epidemiology II
- Cardiovascular Health Research Unit
- University of Washington
- Department of Genetics
- University of Groningen
- University of Edinburgh
- Merck Research Laboratories
- Program in Personalized Medicine
- University of Maryland, Baltimore
- National Research Council of Italy
- Department of Biomedical Sciences
- University of Sassari
- Center for Statistical Genetics
- University of Michigan, Ann Arbor
- Institute for Maternal and Child Health
- IRCCS Ospedale Infantile Burlo Garofolo - Trieste
- Public Health Sciences Division
- Fred Hutchinson Cancer Research Center
- Department of Epidemiology
- Institute for Community Medicine
- University of Greifswald
- Division of Genetics and Cell Biology
- San Raffaele Scientific Institute
- Department of Clinical Medical Sciences,Surgical and Health
- University of Trieste
- Department of Pediatrics
- University of California at Los Angeles
- Department of Medical Genetics
- University of Lausanne
- Swiss Institute of Bioinformatics
- Vrije Universiteit Amsterdam
- Department of Twin Research and Genetic Epidemiology
- King's College London
- National Institute for Health Research (NIHR)
- Guy's and St Thomas' NHS Foundation Trust
- Icelandic Heart Association
- University of Iceland
- Longitudinal Studies Section
- National Institutes of Health
- University of Toronto
- Department of Epidemiology
- University of California at Irvine
- Division of Clinical Epidemiology and Aging Research
- German Cancer Research Center
- Department of Gynaecology and Obstetrics
- Friedrich-Alexander University Erlangen-Nürnberg
- Division of Epidemiology
- Vanderbilt University
- Human Genetics Group
- Spanish National Cancer Research Centre
- Centro de Investigación en Red de Enfermedades Raras (CIBERER)
- City of Hope National Med Center
- Division of Epidemiology
- Mayo Clinic Rochester, MN
- Department of Oncology
- University of Helsinki
- Human Genetics Center
- University of Texas Health Science Center at Houston
- Human Genome Sequencing Center
- Baylor College of Medicine
- Department of Radiation Oncology
- Hannover Medical School
- University of Copenhagen
- Department of Clinical Biochemistry
- Department of Genetics
- University of Oslo
- Institute of Clinical Medicine
- Robert Bosch Foundation
- Institute of Clinical Pharmacology
- University of Tübingen
- Division of Preventive Oncology
- Ruhr University Bochum
- Division of Molecular Genetic Epidemiology
- Molecular Biology of Breast Cancer
- Heidelberg University
- Medical Genetics Section
- Institute for Population Health Sciences and Informatics
- Division of Cancer Epidemiology and Genetics
- University of Oxford
- Department of Genetics
- Queensland Institute of Medical Research
- Department of Laboratory Medicine and Pathology
- Section of Preventive Medicine
- Section of Endocrinology
- Sheffield Cancer Research
- University of Sheffield
- Department of Medical Epidemiology and Biostatistics
- Karolinska Institutet
- Division of Epidemiology and Community Health
- University of Minnesota Twin Cities
- Department of Human Genetics
- Leiden University
- Department of Pathology
- Gynaecology Research Unit
- Non-communicable Disease Epidemiology Department
- London School of Hygiene and Tropical Medicine
- Centre for Cancer Genetic Epidemiology
- Division of Hematology and Oncology
- Survey Research Center
- Department of Cancer Epidemiology/Clinical Cancer Registry
- University of Hamburg
- Institute for Medical Biometrics and Epidemiology
- Laboratory of Epidemiology and Population Sciences
- Division of Genetics and Epidemiology
- Institute of Cancer Research
- Division of Cancer Studies
- Centre for Epidemiology and Biostatistics
- Cancer Epidemiology Centre
- Cancer Council Victoria
- Department of Medicine
- McGill University
- Division of Clinical Epidemiology
- Division of Endocrinology,Diabetes and Metabolism
- Cedars-Sinai Medical Center
- School of Engineering and Natural Sciences
- Renal and Cardiovascular Epidemiology
- Université Paris-Saclay
- Department of Preventive Medicine
- University of Southern California
- Molecular Genetics of Breast Cancer
- Musculoskeletal Research Programme
- University of Aberdeen
- Interfaculty Institute for Genetics and Functional Genomics
- Department of Nutrition
- State Key Laboratory of Medical Genomics
- Shanghai Jiao Tong University
- Department of Genetics and Pathology
- Pomeranian Medical University in Szczecin
- Hebrew SeniorLife Institute for Aging Research
- Prosserman Centre for Health Research
- Division of Epidemiology
- Faculty of Medicine
- University of Split
- Cancer Center
- University of Eastern Finland
- School of Medicine
- Imaging Center
- German Center for Diabetes Research
- Department of Clinical Molecular Biology
- Flanders Institute for Biotechnology
- Laboratory for Translational Genetics
- KU Leuven
- Center for Human Genetics
- Wake Forest University
- Division of Gynaecology and Obstetrics
- Technical University of Munich
- Department of Medicine I
- Ludwig Maximilian University of Munich
- German Centre for Cardiovascular Research
- Laboratory of Neurogenetics
- Department of Obstetrics and Gynecology
- University of Pittsburgh
- Department of Clinical and Translational Science
- University of Glasgow
- FIRC Institute of Molecular Oncology
- Institute of Clinical Chemistry and Laboratory Medicine
- Department of Epidemiology
- Group Health Cooperative
- Laboratory of Cancer Genetics and Tumor Biology
- University of Oulu
- Northern Finland Laboratory Centre NordLab
- Unit of Molecular Bases of Genetic Risk and Genetic Testing
- IRCCS Fondazione Istituto Nazionale per lo studio e la cura dei tumori - Milano
- Medical Genetics Institute
- Division of Cancer Epidemiology
- Intramural Research Program
- Antoni van Leeuwenhoek Hospital
- Division of Molecular Gyneco-Oncology
- University of Cologne
- Center of Familial Breast and Ovarian Cancer
- Center for Integrated Oncology
- Laval University
- Department of Pathology
- University of Melbourne
- Dept. of Genetic Epidemiology
- Division of Breast Cancer Research
- Department of Molecular Virology
- Ohio State University
- Oxford University Hospitals NHS Foundation Trust
- Icelandic Cancer Society
- Division of Nephrology and Hypertension
- Division of Clinical Pharmacology
- Department of Biological Psychology
- Department of Endocrinology
- Molecular Diagnostics Laboratory
- Demokritos National Centre for Scientific Research
- Department of Obstetrics and Gynecology
- Department of Epidemiology
- Department of Biostatistics
- Department of Paediatrics
- University of Tartu
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