Abstract
Parkinson's disease (PD) is a progressive neurodegenerative disorder influenced by both environmental and genetic risk factors. This study investigates the prevalence of the LRRK2 G2019S mutation in a Libyan population of 140 PD patients and 58 controls. Genetic analysis of blood samples revealed that 19.5% of PD patients carry the G2019S mutation, indicating a genetic association with the disease. The study highlights the G2019S mutation as a potential genetic risk factor for PD in Libya and emphasizes the importance of genetic screening for better understanding and management of the disease.
| Original language | English |
|---|---|
| Pages (from-to) | 664-667 |
| Number of pages | 4 |
| Journal | Journal of Parkinson's Disease |
| Volume | 15 |
| Issue number | 3 |
| Early online date | Mar 2025 |
| DOIs | |
| Publication status | Published - May 2025 |
Keywords
- G2019s
- Lrrk2
- Neurogenetics
- North Africa
- Parkinson's disease