In-vitro and in-silico evaluation of rue herb for SARS-CoV-2 treatment

Keyphrases

• In Silico Evaluation 100%
• SARS-CoV-2 Treatment 100%
• Rue Herb 100%
• Spike Glycoprotein 80%
• Amentoflavone 40%
• Vitamin P 40%
• Daphnoretin 40%
• Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) 40%
• Agathisflavone 40%
• COVID-19 20%
• Associated Complications 20%
• Membrane Fusion 20%
• Behavioural Interactions 20%
• SARS-CoV-2 Infection 20%
• Screening Process 20%
• Movement Patterns 20%
• Binding Energy 20%
• In Vitro Assay 20%
• Fatality 20%
• Potential Interaction 20%
• Potential Inhibitors 20%
• Inhibitory Properties 20%
• Screening Approach 20%
• Molecular Mechanics Generalized Born Surface Area (MM-GBSA) 20%
• IC50 Value 20%
• Hit Compound 20%
• Functional Behavior 20%
• Cytotoxic Concentration 20%
• P-glycoprotein Inhibitor 20%
• Functional Potential 20%
• Toxicity Profile 20%
• Herb Extract 20%
• Pharmacokinetic Profile 20%
• ADMET Analysis 20%
• Viral Activity 20%
• Natural Small Molecules 20%
• Viral Spike 20%
• Ruta Graveolens 20%
• ACE2 Receptor 20%
• Compound Stability 20%
• CC50 20%
• Betacoronavirus 20%
• Therapeutic Interventions 20%
• Potential Spike 20%
• Pharmacogenetic Testing 20%
• Molecular Docking Simulation 20%

Pharmacology, Toxicology and Pharmaceutical Science

• SARS Coronavirus 100%
• Ruta graveolens 100%
• Glycoprotein 50%
• Infection 33%
• Daphnoretin 33%
• Bioflavonoid 33%
• Rutin 33%
• Amentoflavone 33%
• Virus 33%
• Pandemic 16%
• IC50 16%
• Virtual Screening 16%
• Fatality 16%
• Receptor 16%
• Molecular Docking Simulations 16%
• Pharmacokinetics 16%
• Virus Spike Protein 16%
• Absorption-Distribution-Metabolism-Excretion Toxicity 16%
• Betacoronavirus 16%