Abstract
Although diastolic function is known to be impaired by aging, aerobic exercise training has been shown to decrease this detrimental effect. However, little is known about the effects of short exercise training interventions on diastolic function in older compared to young healthy individuals.
PURPOSE: To compare diastolic function in older and young healthy men and women before, midway, and immediately after a 12-week aerobic exercise training program.
METHODS: Doppler-derived resting echocardiographic indices of left ventricular function were measured at baseline, six weeks, and twelve weeks of an aerobic training program. Measurements included diastolic flow velocity ratio (E/A) and isovolumetric relaxation time (IVRT). Fourteen older (O) (8 men and 6 women; 68 ± 6.9 yrs.) and 17 young (Y) (9 men and 8 women; 24 ± 4.9 yrs.) healthy sedentary individuals took part in an aerobic training program on a cycle ergometer (3 x week, 45 min/session, at a power output representing 70% VO2max; training intensity was adjusted at three weeks intervals).
RESULTS: Exercise training resulted in a 20% increase in VO2max in older (Pre: 2.05 ± 0.49 L·min-1; Post: 2.55 ± 0.62 L·min-1; p<0.05) and a 16% increase in VO2max in young (Pre: 3.23 ± 0.72 L·min-1; Post: 3.84 ± 0.73 L·min-1; p<0.05). The exercise training intervention did not affect the E/A ratio neither in older (Pre: 1.0 ± 0.3; Mid: 1.0 ± 0.3; Post: 1.0 ± 0.2; p>0.05), nor in young individuals (Pre: 2.0 ± 0.7; Mid: 1.9 ± 0.5; Post: 2.0 ± 0.5; p>0.05). However, the IVRT was significantly lowered at post- compared to pre- and mid-training in both older (Pre 108.3±17.5; Mid: 107.7 ± 25.21.7; Post: 95.8 ± 15.4 ms) and young individuals (Pre: 73.1 ± 8.6 ms; Mid: 76.8 ± 9.6; Post: 70.6 ± 9.1 ms).
CONCLUSION: This study demonstrated that a short-duration (12 weeks) aerobic training program, that improved cardiovascular fitness (i.e., increased VO2max), resulted in improved diastolic function as expressed by a faster IVRT. Importantly, older individuals showed a similar ability to adapt as compared to their younger counterparts.
PURPOSE: To compare diastolic function in older and young healthy men and women before, midway, and immediately after a 12-week aerobic exercise training program.
METHODS: Doppler-derived resting echocardiographic indices of left ventricular function were measured at baseline, six weeks, and twelve weeks of an aerobic training program. Measurements included diastolic flow velocity ratio (E/A) and isovolumetric relaxation time (IVRT). Fourteen older (O) (8 men and 6 women; 68 ± 6.9 yrs.) and 17 young (Y) (9 men and 8 women; 24 ± 4.9 yrs.) healthy sedentary individuals took part in an aerobic training program on a cycle ergometer (3 x week, 45 min/session, at a power output representing 70% VO2max; training intensity was adjusted at three weeks intervals).
RESULTS: Exercise training resulted in a 20% increase in VO2max in older (Pre: 2.05 ± 0.49 L·min-1; Post: 2.55 ± 0.62 L·min-1; p<0.05) and a 16% increase in VO2max in young (Pre: 3.23 ± 0.72 L·min-1; Post: 3.84 ± 0.73 L·min-1; p<0.05). The exercise training intervention did not affect the E/A ratio neither in older (Pre: 1.0 ± 0.3; Mid: 1.0 ± 0.3; Post: 1.0 ± 0.2; p>0.05), nor in young individuals (Pre: 2.0 ± 0.7; Mid: 1.9 ± 0.5; Post: 2.0 ± 0.5; p>0.05). However, the IVRT was significantly lowered at post- compared to pre- and mid-training in both older (Pre 108.3±17.5; Mid: 107.7 ± 25.21.7; Post: 95.8 ± 15.4 ms) and young individuals (Pre: 73.1 ± 8.6 ms; Mid: 76.8 ± 9.6; Post: 70.6 ± 9.1 ms).
CONCLUSION: This study demonstrated that a short-duration (12 weeks) aerobic training program, that improved cardiovascular fitness (i.e., increased VO2max), resulted in improved diastolic function as expressed by a faster IVRT. Importantly, older individuals showed a similar ability to adapt as compared to their younger counterparts.
| Original language | English |
|---|---|
| Pages (from-to) | 49-49 |
| Number of pages | 1 |
| Journal | Medicine and Science in Sports and Exercise |
| DOIs | |
| Publication status | Published - 1 Jun 2016 |
| Externally published | Yes |
| Event | Annual Meeting of the American-College-of-Sports-Medicine (ACSM) - Boston, Morocco Duration: 31 May 2016 → 4 Jun 2016 |