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Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes

  • Xiaofeng Zheng
  • , Qing Wei Calvin Ho
  • , Minni Chua
  • , Olga Stelmashenko
  • , Xin Yi Yeo
  • , Sneha Muralidharan
  • , Federico Torta
  • , Elaine Guo Yan Chew
  • , Michelle Mulan Lian
  • , Jia Nee Foo
  • , Sangyong Jung
  • , Sunny Hei Wong
  • , Nguan Soon Tan
  • , Nanwei Tong
  • , Guy A. Rutter
  • , Markus R. Wenk
  • , David L. Silver
  • , Per Olof Berggren
  • , Yusuf Ali*
  • *Corresponding author for this work
  • Nanyang Technological University
  • Singapore General Hospital
  • Sichuan University
  • Agency for Science, Technology and Research, Singapore
  • National University of Singapore
  • Imperial College London
  • Université de Montreál
  • Duke-National University
  • Karolinska Institutet

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Biochemistry, Genetics and Molecular Biology