Abstract
In this work, we present a pre-analytical module based on the combination of microfluidic and electroacoustic technologies to intercept and sort submicron biological particles. It is composed by assembling a lithium niobate (LN) substrate for acoustic function and a micromachined glass substrate for microfluidic channel. The interference between the two surface acoustic waves (SAWs) generated by inter digital transducers (IDTs) create a distribution of an acoustic radiation force (ARF). This force affects differently particles depending on their physical proprieties. The device is powered by an electronic circuit with a phase shifter to move the node of the standing surface acoustic wave (SSAW) along the channel width. When the device is powered at resonance frequency, experience has shown a submicron particles alignement at a fixed position along the channel. By shifting the SSAW phase, the particles are driven to one of the three channel outlets.
| Original language | English |
|---|---|
| Title of host publication | Sensors And Electronic Instrumentation Advances (seia' 19) |
| Editors | SY Yurish |
| Publisher | Int Frequency Sensor Assoc-Ifsa |
| Pages | 299-300 |
| Number of pages | 2 |
| ISBN (Electronic) | 978-84-09-14413-6 |
| Publication status | Published - 2019 |
| Externally published | Yes |
| Event | 5th International Conference on Sensors and Electronic Instrumentation Advances (SEIA) - Adeje, Spain Duration: 25 Sept 2019 → 27 Sept 2019 |
Conference
| Conference | 5th International Conference on Sensors and Electronic Instrumentation Advances (SEIA) |
|---|---|
| Country/Territory | Spain |
| City | Adeje |
| Period | 25/09/19 → 27/09/19 |
Keywords
- Acoustic particle manipulation
- Acoustic radiation force
- Continuous sorting system
- Extracellular vesicles
- Microfluidic MEMS
- Standing surface acoustic wave