TY - GEN
T1 - Chain of Thought Strategy for Smaller LLMs for Medical Reasoning
AU - Shah, Hurmat Ali
AU - Househ, Mowafa
N1 - Publisher Copyright:
© 2025 The Authors.
PY - 2025/5/15
Y1 - 2025/5/15
N2 - This paper investigates the application of Chain of Thought (CoT) reasoning to enhance the performance of smaller language models in medical question-answering tasks. By leveraging CoT prompting strategies, we aim to improve model accuracy and interpretability, especially in resource-constrained settings. Using the PubMedQA dataset, we demonstrate how CoT helps smaller models break down complex medical queries into sequential steps, enabling more structured reasoning. While these models still face challenges in handling highly specialized medical content, CoT significantly improves their viability for healthcare applications. Our findings suggest that further optimization through methods like retrieval-augmented generation could further close the performance gap between smaller and larger models.
AB - This paper investigates the application of Chain of Thought (CoT) reasoning to enhance the performance of smaller language models in medical question-answering tasks. By leveraging CoT prompting strategies, we aim to improve model accuracy and interpretability, especially in resource-constrained settings. Using the PubMedQA dataset, we demonstrate how CoT helps smaller models break down complex medical queries into sequential steps, enabling more structured reasoning. While these models still face challenges in handling highly specialized medical content, CoT significantly improves their viability for healthcare applications. Our findings suggest that further optimization through methods like retrieval-augmented generation could further close the performance gap between smaller and larger models.
KW - Chain of Thought
KW - Large Language Models
KW - Medical Reasoning
UR - https://www.scopus.com/pages/publications/105005816935
U2 - 10.3233/SHTI250466
DO - 10.3233/SHTI250466
M3 - Conference contribution
C2 - 40380574
AN - SCOPUS:105005816935
T3 - Studies in Health Technology and Informatics
SP - 783
EP - 787
BT - Intelligent Health Systems - From Technology to Data and Knowledge, Proceedings of MIE 2025
A2 - Andrikopoulou, Elisavet
A2 - Gallos, Parisis
A2 - Arvanitis, Theodoros N.
A2 - Austin, Rosalynn
A2 - Benis, Arriel
A2 - Cornet, Ronald
A2 - Chatzistergos, Panagiotis
A2 - Dejaco, Alexander
A2 - Dusseljee-Peute, Linda
A2 - Mohasseb, Alaa
A2 - Natsiavas, Pantelis
A2 - Nakkas, Haythem
A2 - Scott, Philip
PB - IOS Press BV
T2 - 35th Medical Informatics Europe Conference, MIE 2025
Y2 - 19 May 2025 through 21 May 2025
ER -