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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
Kirti S. Prabhu
, Fareed Ahmad
, Shilpa Kuttikrishnan
, Rari Leo
, Tayyiba Akbar Ali
, Mahmoud Izadi
, Jericha M. Mateo
, Majid Alam
, Aamir Ahmad
, Ammira S. Al-Shabeeb Akil
, Ajaz A. Bhat
, Joerg Buddenkotte
,
Ehsan Pourkarimi
, Martin Steinhoff
, Shahab Uddin
*
*
Corresponding author for this work
Genomics and Translational Biomedicine
Hamad Medical Corporation
Hamad bin Khalifa University
Sidra Medical and Research Center
Weill Cornell Medicine-Qatar
Qatar University
Cornell University
Research output
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Contribution to journal
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Article
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peer-review
6
Citations (Scopus)
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Keyphrases
Bortezomib
100%
Skin Cancer Cells
100%
S-phase Kinase-associated Protein 2 (Skp2)
100%
Mitochondrial Permeability
16%
A431
16%
Cure Rate
8%
Nucleoporin p62
8%
CEP-1
8%
Basal Cell Carcinoma
8%
Immunology and Microbiology
Skin Cancer Cell Line
40%
Mitochondrial Permeability
40%
Bcl-2
20%
Apoptosis
20%
Basal Cell
20%
Pharmacology, Toxicology and Pharmaceutical Science
Bortezomib
100%
Nucleoporin
8%
Cytochrome C
8%
Basal Cell Carcinoma
8%
Biochemistry, Genetics and Molecular Biology
Mitochondrial Permeability
40%
Cytochrome C
20%
Bcl-2
20%
Nucleoporin
20%