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An ensemble of deep learning models with falcon optimization assisted diabetic retinopathy diagnosis on retinal fundus images

  • Indresh Kumar Gupta
  • , Shruti Patil*
  • , Ketan Kotecha
  • , Swati Srivastava
  • , Ahmed Farouk
  • , Joel J.P.C. Rodrigues
  • *Corresponding author for this work
  • Pranveer Singh Institute of Technology
  • Lusófona University
  • Symbiosis International University
  • Symbiosis Centre for Applied Artificial Intelligence, Pune
  • GLA University
  • Hurghada University
  • Universidade Federal do Piauí

Research output: Contribution to journal › Article › peer-review

Abstract

Diabetic Retinopathy (DR) is a prominent results of diabetes mellitus that causes abnormalities lesions in retina. If not identified at early, it may progress to complete loss of vision. Unfortunately, DR is an irreversible, and treatment only sustains existing vision. Timely detection and accurate treatment of DR can considerably decrease the chance of blindness. Manual diagnosis of DR in retinal fundus images (RFIs) by ophthalmologist is time consuming, costly and laborious tasks with a higher risk of misdiagnosis. Recently, Deep learning (DL) has gained popularity and shown remarkable performance particularly in medical image analysis and classification. Convolutional neural networks (CNNs) are increasingly being used as a DL approach in medical image analysis, and they are very efficient. This manuscript offers the design of Falcon Optimizer with Ensemble of Deep Learning Algorithm Assisted Diabetic Retinopathy Diagnosis Model (FOEDLA-DRDM) system on RFIs. The FOEDLA-DRDM system employs a Wiener filtering (WF) based preprocessing approach to eliminate noise from images. Following this, FOEDLA-DRDM system leverages the SE-DenseNet method to generate the feature vectors. For DR recognition FOEDLA-DRDM system applies an ensemble approach that combines - AutoEncoder, long short-term memory (LSTM), and deep belief network (DBN). Finally, Falcon Optimizer (FO) adjusts the hyperparameter values of the ensemble approach, giving rise to classification efficiency. The FOEDLA-DRDM system is validated by simulating it on a Kaggle DR dataset, with results being measured according to various criteria. The simulation findings showcase the effectiveness of the FOEDLA-DRDM system in diagnosis of DR.

Original languageEnglish
Article number27138
JournalScientific Reports
Volume16
Issue number1
Early online dateJun 2026
DOIs
Publication statusE-pub ahead of print - Jun 2026
Externally publishedYes

Keywords

  • Autoencoder
  • Deep belief network
  • Diabetic retinopathy
  • Falcon optimizer
  • Retinal fundus image

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