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Dive into the research topics where Issam Hmila is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 1 Active
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QBRI-CORE-000016: Oncogenic signaling pathways in cancer mechanisms and drug discovery
Katanaev, V. (Lead Principal Investigator) & Hmila, I. (Post Doctoral Fellow)
1/01/25 → 31/12/27
Project: Experimental Development/Translation Research
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DNA APTAMERS AND COMPOSITIONS TARGETING ALPHA-SYNUCLEIN AND METHODS OF MAKING AND USING SAME
Hmila, I. (Inventor), Majbour, N. K. (Inventor) & El-Agnaf, O. (Inventor), 18 Apr 2024, IPC No. C12N 15/ 115 A I, Patent No. US2024124883, Priority date 19 Feb 2022, Priority No. US202218278255Research output: Patent
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ENGINEERED PICOBODY TO ALPHA SYNUCLEIN
Kolatkar, P. R. (Inventor), Islam, Z. (Inventor), Hmila, I. (Inventor), Vaikath, N. (Inventor) & El-Agnaf, O. (Inventor), 15 Feb 2024, IPC No. G01N 33/ 68 A I, Patent No. US2024052022, Priority date 14 Aug 2023, Priority No. US202318233733Research output: Patent
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Structural insights into the unique recognition module between α-synuclein peptide and nanobody
Islam, Z., Vaikath, N. N., Hmila, I., El-Agnaf, O. M. A. & Kolatkar, P. R., Feb 2024, In: Protein Science. 33, 2, e4875.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Novel engineered nanobodies specific for N-terminal region of alpha-synuclein recognize Lewy-body pathology and inhibit in-vitro seeded aggregation and toxicity
Hmila, I., Vaikath, N. N., Majbour, N. K., Erskine, D., Sudhakaran, I. P., Gupta, V., Ghanem, S. S., Islam, Z., Emara, M. M., Abdesselem, H. B., Kolatkar, P. R., Achappa, D. K., Vinardell, T. & El-Agnaf, O. M. A., Aug 2022, In: FEBS Journal. 289, 15, p. 4657-4673 17 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies
Gupta, V., Sudhakaran, I. P., Islam, Z., Vaikath, N. N., Hmila, I., Lukacsovich, T., Kolatkar, P. R. & El-Agnaf, O. M. A., Nov 2020, In: PLoS ONE. 15, 11 November, e0241773.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus)