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Biography
Dr. Cong-Yi (CY) Wang is the Scientific Director of the Diabetes Research Center at the Qatar Biomedical Research Institute. He earned his Ph.D. in Medical Immunology from Tongji Medical College, Huazhong University of Science and Technology, China. He completed postdoctoral training in population genetics, genomics, and immunology of type 1 diabetes (T1D) at the University of Florida under Dr. Noel Maclaren, a pioneer in endocrinology and metabolism.
Dr. Wang was later recruited as a tenure-track Assistant Professor at the Center for Biotechnology and Genomic Medicine, Medical College of Georgia (now Augusta University), where he studied genetic and environmental factors influencing T1D risk. He was also appointed Scientific Director of the Georgia Exoteric and Molecular Laboratories at the Medical College of Georgia Health Science Center after his promotion.
In 2014, Dr. Wang was recruited by the Tongji Medical College, Huazhong University of Science and Technology, as a tenured professor. At Tongji Hospital, he established the Center for Biomedical Research, Tongji Biobank, and the Tongji SPF Animal Center. He served as Director of the Center for Biomedical Research, Tongji Biobank, and the National Health Commission Key Laboratory of Respiratory Diseases, as well as Associate Director of Sponsored Program Administration.
Dr. Wang’s research focuses on the genetic and epigenetic mechanisms of type 1 and type 2 diabetes. He has published > 240 peer reviewed scientific papers with 20 patents. His team investigates the crosstalk between different cell types and metabolic organs, by which he aims to identify diet-derived metabolites or small molecules that could be employed to prevent or treat metabolic disorders such as obesity and insulin resistance.
Research Interests
- The genetic and epigenetic factors underlying metabolic and autoimmune disorders
- Diet-derived metabolites or small molecules for the prevention/intervention or treatment of metabolic or autoimmune disorders
- The crosstalk between metabolic organs or organelles within the cells and their relevance to the development of metabolic disorders
- The mechanisms underlying the recurrence of obesity following weight loss
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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QBRI-CORE-000019: Kynurenine modulates adipose beiging process in the setting of obesity and type 2 diabetes
Wang, C.-Y. (Lead Principal Investigator)
23/06/25 → 31/12/27
Project: Experimental Development/Translation Research
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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)
Liu, Y. C., Zhao, J. W., Yue, X. T., Chen, Q. J., Rong, S. J., Liu, S. W., Sun, F., Yang, C. L. & Wang, C. Y., Feb 2026, In: International Journal of Molecular Medicine. 57, 2, 49.Research output: Contribution to journal › Review article › peer-review
Open Access -
miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis
Wang, C., Hou, Y., Zhang, M., Wang, J., Chu, X., Liang, M., Sun, C., Xie, J., Zhang, J. & Wang, C. Y., Jan 2026, In: Diabetes. 75, 1, p. 22-36 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Ubc9-Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9-p16 Axis
Xie, H., Gao, Z., Liu, X., Zhang, S., Wang, Y., Gao, J., Qi, P., Zhang, L., Zhao, J., Xiong, T., Huang, T., Song, J., Yu, Q., Zhang, S., Liu, Y., Yang, P., Al-Motawa, M. S., Gong, Q., Dong, J. & Yin, H. & 3 others, , 5 Jan 2026, In: Advanced Science. 13, 1, e10240.Research output: Contribution to journal › Article › peer-review
Open Access -
Adipose progenitor cell-derived extracellular vesicles suppress macrophage M1 program to alleviate midlife obesity
Zhou, Q., Gao, J., Wu, G., Wang, C., Yang, Y., Huang, T., Wang, Y., Yue, T., Gao, Z., Xie, H., Xiong, F., Xiang, K., Yong, T., Zhang, W., Zhang, T., Kong, W., Chen, C., Zhang, S., Yu, Q. & Fan, X. & 3 others, , 20 Mar 2025, In: Nature Communications. 16, 1, 22 p., 2743.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
AI-Assisted Hypothesis Generation to Address Challenges in Cardiotoxicity Research: Simulation Study Using ChatGPT With GPT-4o
Li, Y., Gu, T., Yang, C., Li, M., Wang, C.-Y., Yao, L., Gu, W. & Sun, D., 15 May 2025, In: Journal of Medical Internet Research. 27, 19 p., e66161.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus)