Projects per year
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Collaborations and top research areas from the last five years
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QBRI-CORE-000015: Identification and Validation of Transcription Factor Variants in Gestational Diabetes
Al-Siddiqi, H. H. A. A. (Lead Principal Investigator), Diane, A. (Post Doctoral Fellow) & Abdulmuumin, R. (Post Doctoral Fellow)
1/01/25 → 31/12/27
Project: Experimental Development/Translation Research
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EX-QNRF-NPRPS-54: Therapeutic potential of DNAJB3/HSP-40 as a novel biomarker for obesity-induced insulin resistance and diabetes
Kolatkar, P. R. (Lead Principal Investigator), Diane, A. (Principal Investigator), Assistant-1, R. (Research Assistant), Assistant-2, R. (Research Assistant), Assistant-3, R. (Research Assistant), Ashawesh, D. K. (Principal Investigator), Dukhan, D. K. M. (Principal Investigator), Elkum, D. N. (Principal Investigator) & Moustaid-Moussa, P. N. (Principal Investigator)
12/05/19 → 10/08/23
Project: Experimental Development/Translation Research
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Endoplasmic reticulum stress in pancreatic β-cell dysfunctionality and diabetes mellitus: a promising target for generation of functional hPSC-derived β-cells <i>in vitro</i>
Diane, A., Allouch, A., Mu-U-Min, R. B. A. & Al-Siddiqi, H. H., 20 Jun 2024, In: Frontiers in Endocrinology. 15, 8 p., 1386471.Research output: Contribution to journal › Review article › peer-review
10 Citations (Scopus) -
Both MAFA and MAFB are required for acquisition of glucose-stimulated insulin secretion (GSIS) in human pluripotent stem cell-derived islets
Allouch, A., Diane, A., Abdulmuumin, R. & Al-Siddiqi, H. H., Sept 2023, In: Diabetologia. 66, SUPPL 1, p. S97-S98 2 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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DNAJB3 attenuates ER stress through direct interaction with AKT
Islam, Z., Diane, A., Khattab, N., Dehbi, M., Thornalley, P. & Kolatkar, P. R., Aug 2023, In: PLoS ONE. 18, 8 AUGUST, e0290340.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Exendin-4 enhances GSIS through upregulation of MAFA and mitochondrial oxidative phosphorylation machinery genes in hPSC-derived beta cells
Diane, A., Mu-u-min, R. B. A. & Al-Siddiqi, H. H., Sept 2022, In: Diabetologia. 65, SUPPL 1, p. S197-S198 2 p.Research output: Contribution to journal › Meeting Abstract › peer-review
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Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone
Diane, A., Mahmoud, N., Bensmail, I., Khattab, N., Abunada, H. A. & Dehbi, M., 24 Nov 2020, In: Scientific Reports. 10, 1, 20482.Research output: Contribution to journal › Article › peer-review
Open Access24 Citations (Scopus)